Catherine Ann Keener born March 23 1959 is an American actress Considered one of the independent film industrys most reliable performers Keener is known for portraying disgruntled and melancholic yet sympathetic women in independent films as well as supporting roles in studio films She has been twice nominated for the Academy Award for Best Supporting Actress for Being John Malkovich 1999 and for her portrayal of author Harper Lee in Capote 2005 Keener also appeared in the films The 40YearOld Virgin 2005 Into the Wild 2007 Synecdoche New York 2008 and Get Out 2017 which were all well received by critics Keener is the muse of director Nicole Holofcener having appeared in each of Holofceners first five films She also appeared in each of director Tom DiCillos first four films and three films directed by Spike Jonze From 2018 to 2020 she starred in the Showtime dramedy series Kidding From Wikipedia the free encyclopedia