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Genetic Engineering has produced a generation of super-babies, but the technology is not perfect. It has also produced horribly deformed children who suffer from Genetic Rejection Syndrome (GRS), a condition which makes them even stronger, faster, smarter than the super-babies and more deadly to boot. Detective Ray Venable (Gary Cole), is in charge of the team that must hunt down the most severe GRS cases, but he carries with him a dark secret. Years before, he and his wife Marie (Lynda Boyd) had a child, Dylan (Jason Gray-Stanford), who developed GRS and who they secretly sent away to a home. Now, Ray suspects that Dylan is behind a series of brutal murders and is closing in on his old family. The only way Ray can stop him is to take a genetic serum that will make him more like the son he rejected.